

Standardized periapical radiographs were taken immediately after implant placement and at every month up to 1 year. Three implants were placed on either side of the mandible with either bone adhesive (BA), bovine bone mineral (BBM), or no biomaterial (negative control ). Twenty-six mixed breed hound dogs were included in this study. This was a randomized, controlled, three arm, prospective study. The purpose of this study was to evaluate the maintenance of crestal bone/material level by standardized radiographs.

A novel bone adhesive (tetracalcium phosphate and O-phospho-L-serine) has been developed as an osteoconductive, biodegradable bone-adherent material.
